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TROPONIN C1
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DeCS
Descriptor
English
:
Troponin C
Descriptor
Spanish
:
Troponina C
Descriptor
Portuguese
:
Troponina C
Synonyms
English
:
Troponin C1
Troponin C2
Troponin-C
Tree Number:
D05.500.945.900
D05.750.078.730.825.900
D12.776.157.125.900
D12.776.210.500.910.900
D12.776.220.525.825.900
Definition
English
:
A
TROPONIN
complex subunit that binds
calcium
and help regulate calcium-dependent
muscle contraction
. There are two
troponin C
subtypes:
troponin
C1 and C2.
Troponin
C1 is skeletal and cardiac type whereas
troponin
C2 is skeletal type.
Troponin
C1 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and
mutations
in
troponin
C1 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
Indexing Annotation
English
:
TROPONIN I
&
TROPONIN T
are also available
History Note
English
:
97; was TROPONIN C (NM) 1975-96
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
33042
Unique Identifier:
D019209
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS